The synthesis of dienecarbamates as adapt prodrug models

Article abstract of DOI:10.1080/00397919708004108

An efficient process utilizing a modified Curtius rearrangement was developed for the synthesis of carbamate substrates 1a-c and 2. The potential of these compounds as prodrug structures 3 for antibody-directed abzyme prodrug therapy (ADAPT) has been chem

Full text of DOI:10.1080/00397919708004108

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Synthetic Communications: An
International Journal for Rapid
Communication of Synthetic
Organic Chemistry
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The Synthesis of
Dienecarbamates as Adapt
Prodrug Models
G. Xiaobo Ma a , Robert A. Batey a , Scott D. Tayler a
, Gabriel Hum a & J. Bryan Jones a
a Department of Chemistry, Lash Miller
Laboratories , University of Toronto , 80 St. George
Street, Toronto, Ontario, M5S 3H6, CANADA
Published online: 21 Aug 2006.
To cite this article: G. Xiaobo Ma , Robert A. Batey , Scott D. Tayler , Gabriel Hum
& J. Bryan Jones (1997) The Synthesis of Dienecarbamates as Adapt Prodrug Models,
Synthetic Communications: An International Journal for Rapid Communication of
Synthetic Organic Chemistry, 27:14, 2445-2453, DOI: 10.1080/00397919708004108
To link to this article: http://dx.doi.org/10.1080/00397919708004108
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