Journal of Medicinal Chemistry p. 1024 - 1031 (1993)
Update date:2022-09-26
Topics:
Chern, Ji-Wang
Lee, Horng-Yuh
Chen, Chien-Shu
Shewach, Donna S.
Daddona, Peter E.
Townsend, Leroy B.
In an effort to develop potent human purine nucleoside phosphorylase (PNP) inhibitors as immunosuppressive and chemotherapeutic agents, several 8-aminoguanine derivatives were synthesized and evaluated as potential PNP inhibitors.These studies were design
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