Intramolecular Heck reactions for the synthesis of the novel antibiotic mensacarcin: Investigation of catalytic, electronic and conjugative effects in the preparation of the hexahydroanthracene core

Article abstract of DOI:10.1002/ejoc.200400786

The intramolecular Heck reaction of the three complex diphenyl substrates rac-2, 5 and rac-6, containing substituents with different electronic and conjugative properties, were examined. The Pd compounds [Pd₂(dba) ₃]/[(tBu)₃