European Journal of Medicinal Chemistry p. 619 - 624 (1991)
Update date:2022-08-04
Topics: THF Yield EtOAc Solvent Organic extract MgSO Chromatography Silica Eluant mp Anal DIBAL-H Negative inotropy PIC50 Recrystallization Nifedipine Amlodipine Felodipine Lacidipine
Alker, D
Cross, P E
To evaluate the effect of introducing unsaturation into the 2-substituent of 1,4-dihydropyridines related to amlodipine (1), a number of alkene and alkyne analogues were prepared and their calcium antagonist activity was assessed.For several series of com
View MoreJinan Yijialian Economic and Trade Development Co., Ltd.
Contact:+86 0531-66729596
Address:jinan
Contact:+86-021-58123769
Address:No.780 of Cailun Road,Zhangjiang Hi-tech Park,Pudong,Shanghai
Hunan Haili Chemical Industry Co.,Ltd.
Contact:+86-731-85521860
Address:No.251, 2nd Section, Furong Road, Changsha,Hunan,China
Zhejiang Rongkai Chemical Technology Co.,Ltd.
Contact:+86-578-8185786
Address:Shangjiang Industrial Zone,Suichang
Contact:0572-2722882
Address:1201,F3,xinghuibandao,
Doi:10.1021/ja01114a515
(1953)Doi:10.1016/j.ica.2011.02.080
(2011)Doi:10.1021/ja01558a026
(1957)Doi:10.1002/ejic.201001332
(2011)Doi:10.1111/j.2042-7158.1990.tb07024.x
(1990)Doi:10.1055/s-0039-1690680
(2019)