2-butyl-4-iodoimidazole-5-carboxaldehyde: A versatile intermediate for the synthesis of highly functionalized imidazoles

Article abstract of DOI:10.1080/00397919308011184

The facile preparation of 2-butyl-4-iodoimidazole-5-carboxaldehyde 1 is described. The versatility of this intermediate in the synthesis of highly functionalized imidazoles is demonstrated with the synthesis of two potent and selective angiotensin II rece

Full text of DOI:10.1080/00397919308011184

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Synthetic Communications: An
International Journal for Rapid
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Organic Chemistry
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2-Butyl-4-iodoimidazole-5-
carboxaldehyde: A Versatile
Intermediate for the Synthesis
of Highly Functionalized
Imidazoles
Steven J. Wittenberger a , Andrew Tasker b , Bryan
K. Sorensen b & B. Gregory Donner b
a Process Chemistry D-45L/AP10, Pharmaceutical
Products Division Abbott Laboratories, One Abbott
Park Road, Abbott Park, IL, 60064-3500
b Cardiovascular Chemistry D-47C/AP10,
Pharmaceutical Products Division, Abbott
Laboratories, One Abbott Park Road, Abbott Park,
IL, 60064-3500
Version of record first published: 23 Sep 2006.
To cite this article: Steven J. Wittenberger, Andrew Tasker, Bryan K. Sorensen &
B. Gregory Donner (1993): 2-Butyl-4-iodoimidazole-5-carboxaldehyde: A Versatile
Intermediate for the Synthesis of Highly Functionalized Imidazoles, Synthetic
Communications: An International Journal for Rapid Communication of Synthetic
Organic Chemistry, 23:22, 3231-3248
To link to this article: http://dx.doi.org/10.1080/00397919308011184
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