THE MANSUMBINANES: OCTANORDAMMARANES FROM THE RESIN OF COMMIPHORA INCISA

Article abstract of DOI:10.1016/0031-9422(86)80027-9

Key Word Index - Commiphora insica; Burseraceae; resin; dammaranes; 16(S),20(R)-dihydroxydammar-24-en-3-one; 17-octanordammaranes; mansumbinone; mansumbinol; 3,4-seco-mansumbinoic acid.The resin of Commiphora incisa (Burseraceae) has yielded three C22 compounds derived by loss of the C-17 side chain from a dammarane triterpene.They have been identified by spectral analysis and chemical modification as 4α,4β,8β,10β,14α-pentamethyl-5α-gon-16-en-3-one (mansumbinone), the corresponding 3-hydroxy compound (mansumbinol) and the derivative 3,4-seco-mansumbinoic acid in which the A-ring has opened between C-3 and C-4.A fourth compound was characterized as 16(S),20(R)-dihydroxydammar-24-en-3-one, a possible precursor of the mansumbinanes.