Folate Analogues. 26. Syntheses of Antifolate Activity of 10-Substituted Derivatives of 5,8-Dideazafolic Acid and of the Poly-γ-glutamyl Metabolites of N10-Propargyl-5,8-Dideazafolic Acid (PDDF)

DOI: 10.1021/jm00159a032

Source and publish data:

Journal of Medicinal Chemistry p. 1754 - 1760 (1986)

Update date:2022-08-05

Topics:

Authors:

Nair, M.G.

Nanavati, Nitin T.

Nair, Indira G.

Kisliuk, Roy L.

Gaumont, Y.

et al. et al.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00159a032

The poly-γ-glutamyl derivatives of N¹⁰-propargyl-5,8-dideazafolic acid (PDDF) with a chain length of up to five glutamate residues were synthesized from N¹⁰-propargyl-5,8-dideazapteroic acid (7) by the solid-phase procedure.These com

Full text of DOI:10.1021/jm00159a032

Products guided by the article

Product name:(S)-2-{4-[(2-Amino-4-oxo-3,4-dihydro-quinazolin-6-ylmethyl)-but-2-ynyl-amino]-benzoylamino}-pentanedioic acid diethyl ester

Cas No:103202-13-7

R&D Labs maybe for 103202-13-7

WUXI HONOR SHINE CHEMICAL CO.,LTD

Contact:+86-510-83593312

Address:No.1699 Huishan avenue,Huishan district,Wuxi ,Jiangsu,China,214177.(Wuxi Huishan Ecomonic Develop Zone )
ZHIJIANG ZENVA SINO COMMERCE AND TRADE CO., LTD.

website:http://www.zenvasino.com

Contact:+86-138-72658998

Address:Shibeishan Road,Zhijiang, Hubei, China
Shanghai chemrole co.,ltd

Contact:021-50278900

Address:No.6,Room 201 ,Lane 299,bisheng road ,shanghai ,china
Shandong Xingshun New Material Co., Ltd.

website:http://www.sd-xingshun.com

Contact:+86-519-86461196/+86-519-86464994

Address:Middle of Luhua East Road, Dingtao District
Anhui Asahikasei Chemical Co., Ltd

Contact:86-551-4259770

Address:No. 88 Linquan Road Hefei Anhui China

Relevant to this article

A NEW AMINE RESOLUTION METHOD AND ITS APPLICATION TO 3-AMINOBENZODIAZEPINES

Doi:10.1016/S0040-4039(00)95771-X
(1987)
Br?nsted acid catalyzed C3-selective propargylation and benzylation of indoles with tertiary alcohols

Doi:10.1055/s-2008-1072584
(2008)
On 2,3,5-Triacetyl-toluene

Doi:10.1007/BF00809164
(1985)
Antifouling activity of meroditerpenoids from the marine brown alga halidrys siliquosa

Doi:10.1021/np070110k
(2008)
Doi:10.1039/jr9570001001
()
Printable cross-linked polymer blend dielectrics. Design strategies, synthesis, microstructures, and electrical properties, with organic field-effect transistors as testbeds

Doi:10.1021/ja801047g
(2008)

Article Doi