A NEW AMINE RESOLUTION METHOD AND ITS APPLICATION TO 3-AMINOBENZODIAZEPINES

DOI: 10.1016/S0040-4039(00)95771-X

Source and publish data:

Tetrahedron Letters p. 521 - 522 (1987)

Update date:2022-08-05

Topics:

Authors:

Rittle, Kenneth E.

Evans, Ben E.

Bock, Mark G.

DiPardo, Robert M.

Whitter, Willie L.

et al. et al.

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Article abstract of DOI:10.1016/S0040-4039(00)95771-X

A new method for the resolution of amines and its application to 3-aminobenzodiazepines 1 is described.The method involves the synthesis and separation of a pair of phenylalanyl amide diastereomers followed by removal of phenylalanine via the Edman degrad

Full text of DOI:10.1016/S0040-4039(00)95771-X

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