Straightforward synthesis of lipophilic thymidine glucopyranosyl monophosphates as models for a drug delivery system across cellular membranes

Article abstract of DOI:10.1080/07328319908044627

O-methyl (3'-6) and (5'-6) thymidinyl gluco- and mannopyranosides and (3'-6) thymidinyl glucofuranose can be synthesised in excellent yields by applying the phosphotriester method. The lipophilic phosphotriesters thus obtained are designed as carriers of nucleoside drugs across cellular membranes.

Full text of DOI:10.1080/07328319908044627

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Nucleosides and Nucleotides
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Straightforward Synthesis of
Lipophilic Thymidine Glucopyranosyl
Monophosphates as Models for a
Drug Delivery System Across Cellular
Membranes
Emilia Belsito a , Angelo Liguori a , Anna Napoli a , Carlo Siciliano a &
Giovanni Sindona a
a Dipartimento di Chimica , Università della Calabria , Via Ponte P.
Bucci, cubo 15/C, I-87030, Arcavacata di Rende (CS), Italy
Published online: 04 Oct 2006.
To cite this article: Emilia Belsito , Angelo Liguori , Anna Napoli , Carlo Siciliano & Giovanni Sindona
(1999) Straightforward Synthesis of Lipophilic Thymidine Glucopyranosyl Monophosphates as Models
for a Drug Delivery System Across Cellular Membranes, Nucleosides and Nucleotides, 18:11-12,
2565-2580, DOI: 10.1080/07328319908044627
To link to this article: http://dx.doi.org/10.1080/07328319908044627
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