Synthesis of a highly hydrophobic cationic lipid and structural and thermodynamic studies for interaction with DNA

DOI: 10.1246/bcsj.20100072

Source and publish data:

Bulletin of the Chemical Society of Japan p. 1010 - 1018 (2010)

Update date:2022-07-30

Topics:

Authors:

Nishimura, Tomoki

Cho, Takeshi

Kelley, Andrew M.

Powell, Magdalena E.

Fossey, John S.

Bull, Steven D.

James, Tony D.

Masunaga, Hiroyasu

Akiba, Isamu

Sakurai, Kazuo

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Article abstract of DOI:10.1246/bcsj.20100072

Synthetic DNA-transfection reagents can overcome safety issues raised by use of viral DNA vectors. One of these candidates is a cationic lipid that can form a supramolecular complex with DNA. We have been working in a series of aromatic diamine lipids wit

Full text of DOI:10.1246/bcsj.20100072

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