Phenethyl ester derivative analogues of the C-terminal tetrapeptide of gastrin as potent gastrin antagonists

DOI: 10.1021/jm00161a012

Source and publish data:

Journal of Medicinal Chemistry p. 2201 - 2206 (1986)

Update date:2022-07-30

Topics: Mass spectrometry (MS)   Pharmacophore   HPLC (high-performance liquid chromatography)   Analogues   Peptide Synthesis   Circular Dichroism (CD)   Structure-Activity Relationship (SAR)   In vitro assay   Gastrin antagonists   C-terminal tetrapeptide   Receptor binding assay   Bioisostere   IC50 (Half-Maximal Inhibitory Concentration)   Gastrin  

Authors:

Martinez

Rodriguez

Bali

Laur