Studies towards the synthesis of bicyclomycin precursors: Synthesis of N,N′-disubstituted 2,5-diketopiperazines in solution and on solid phase

Article abstract of DOI:10.1002/jhet.5570450321

(Chemical Equation Presented) The synthesis of 3-(hydroxyalkyl)-N,N′- disubstituted 2,5-diketopiperazine derivatives - compounds required for the bicyclomycin analogues preparation - has been studied. The use of various oxo components in the Ugi multicomp