4″-benzoylureido-TSAO derivatives as potent and selective non-nucleoside HCMV inhibitors. Structure-activity relationship and mechanism of antiviral action

DOI: 10.1021/jm800050t

Source and publish data:

Journal of Medicinal Chemistry p. 5823 - 5832 (2008)

Update date:2022-07-29

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Authors:

De Castro, Sonia

Peromingo, M. Teresa

Naesens, Lieve

Andrei, Graciela

Snoeck, Robert

Balzarini, Jan

Velázquez, Sonsoles

Camarasa, María-José

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Article abstract of DOI:10.1021/jm800050t

Analogues of the 4″-benzoyl-ureido-TSAO derivative (1) modified at different positions have been prepared and evaluated against wild-type strains of HCMV and murine cytomegalovirus (MCMV) in cell culture. In addition, the activity of the most active deriv

Full text of DOI:10.1021/jm800050t

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