10-Acetyl-10-hydroxyxanthotetralin 8-Glycosides as Angular Chromophore Analogues of Anthracyclines: Synthesis, Redox Properties, Microsomal Oxygen Consumption, and Antileukemic Evaluation

DOI: 10.1021/jm00161a018

Source and publish data:

Journal of Medicinal Chemistry p. 2235 - 2241 (1986)

Update date:2022-08-04

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Authors:

Lown, J. William

Sondhi, Sham M.

Plambeck, James A.

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Article abstract of DOI:10.1021/jm00161a018

10-Acetyl-7,8-dihydroxyxanto<2,3-f>tetralin is obtained by photo-Fries rearrangement of an acylated and double ketal protected tetralin followed by sodium thiocresylate catalyzed rearrangement of the resulting benzoyltetralin.Introduction of the 10-hydrox

Full text of DOI:10.1021/jm00161a018

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