Chemistry of Heterocyclic Compounds p. 1159 - 1163 (1985)
Update date:2022-07-30
Topics:
Zhuk, R. A.
Ludzisha, A. S.
Shpaer, E. G.
Lidak, M. Yu.
Zidermane, A. A.
Meirena, D. V.
1-(3-Phthalidyl)-5-fluorouracils were synthesized by alkylation of 2,4-bis(trimethylsilyl)-5-fluorouracil with substituted 3-bromophthalides, and the rate constants for hydrolysis at pH 8.0-11.5 were determined.The antineoplastic activity of a number of the compounds was established, and it was assumed that there is a relationship between the biological activity and the rate of hydrolysis.
View MoreWuxi Morality Chemical Co., Ltd(expird)
Contact:
Address:B/7F, 321th WuYun Rd, Wanda Plaza, Wuxi City, 214174, China
Changyi Xinxing Technology Development Co., Ltd.
Contact:0086-510-86651065(Time Zone:8),86651656
Address:94 Yingbinxilu WestRoad, Huangtu Town, Jiangyin City, Jiangsu, China
Contact:+86-25-52346955
Address:199,JIANYE ROAD,NANJING,CHINA
Shandong Wanda Organosilicon New Material Co., Ltd
Contact:+86-21-54177116;54302881
Address:R1318 Greenland No. 3 Lane 58 Xinjian East Rd., Minhang
Jiangsu Institute of Ecomones Co., Ltd
website:http://www.jsmone.com
Contact:+86-519-82821700
Address:95 Huanyuan N. Road, Jintan, Jiangsu, China
Doi:10.1016/S0040-4039(01)84598-6
(1985)Doi:10.1016/j.tetasy.2008.04.022
(2008)Doi:10.1080/10587259408039195
(1994)Doi:10.1016/S0040-4020(01)89848-3
(1992)Doi:10.1021/co300104k
(2013)Doi:10.1016/j.tet.2007.07.032
(2007)
