5-Fluoro- and 8-Fluorotrimetoquinol: Selective β2-Adrenoceptor Agonists

DOI: 10.1021/jm00384a015

Source and publish data:

Journal of Medicinal Chemistry p. 86 - 90 (1987)

Update date:2022-08-03

Topics:

Authors:

Clark, Michael T.

Adejare, Adeboye

Shams, Gamal

Feller, Dennis R.

Miller, Duane D.

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Article abstract of DOI:10.1021/jm00384a015

The 5-fluoro and 8-fluoro analogues of trimetoquinol, TMQ, have been synthesized and evaluated for β₂- and β₁-adrenoceptor activity in guinea pig trachea and atria, respectively.The fluoro analogues of TMQ maintained potent β_{2
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Full text of DOI:10.1021/jm00384a015

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