Synthesis of 2-Acetamido-1,5-imino-1,2,5-trideoxy-D-mannitol and of 2-Acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol, a Potent and Specific Inhibitor of a Number of &β-N-Acetylglucosaminidases

Article abstract of DOI:10.1246/cl.1986.1051

The stereochemical outcome of the azide displacement of triflates derived from a piperidin-3-ol depends on the protecting group on the ring nitrogen and allows the synthesis of 2-acetamido-1,5-imino-1,2,5-trideoxy-D-glucitol (a potent and specific inhibit