
Journal of the American Chemical Society p. 236 - 239 (1987)
Update date:2022-07-29
Topics: Experimental terms Chemical terms N-Protected Configurational stability α-amino aldehydes
Lubell, William D.
Rapoport, Henry
A three-step synthesis of N-(9-(9-phenylfluorenyl)-L-alaninal (5) from alanine is described.Exposure to silica or nonnucleophilic base causes no detectable racemization of this α-amino aldehyde.The 9-(9-phenylfluorenyl) N-protecting group also maintains t
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