Inhibition of Aspartic Proteinases by Peptides Containing Lysine and Ornithine Side-Chain Analogues of Statine

DOI: 10.1021/jm00385a010

Source and publish data:

Journal of Medicinal Chemistry p. 286 - 295 (1987)

Update date:2022-09-26

Topics:

Authors:

Salituro, Francesco G.

Agarwal, Nirankar

Hofmann, Theo

Rich, Daniel H.

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Article abstract of DOI:10.1021/jm00385a010

The synthesis of two new analogues of statine are reported corresponding to analogues with the lysine side-chain and the ornithine side chain.These analogues were designed on the basis of substrate specificity and molecular modeling of three-dimensional s

Full text of DOI:10.1021/jm00385a010

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