Synthesis of Potential Dual-Acting Radiation Sensitizer Antineoplastic Agents: 2,2-Dimethylphosphoraziridines Containing 2-Nitroimidazoles or Other Electron-Affinic Moieties

DOI: 10.1021/jm00108a024

Source and publish data:

Journal of Medicinal Chemistry p. 1400 - 1407 (1991)

Update date:2022-08-04

Topics:

Authors:

Perlman, Michael E.

Dunn, Joseph A.

Piscitelli, Thomas A.

Earle, Julie

Rose, William C.

et al. et al.

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Article abstract of DOI:10.1021/jm00108a024

In view of the in vivo demonstrated radiation-potentiating activities of several previously studied 2,2-dimethylphosphoraziridines, six new compounds incorporating the bis(2,2-dimethyl-1-aziridinyl)phosphinyl moiety, together with an electron-affinic grou

Full text of DOI:10.1021/jm00108a024

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