Tetrahedron Letters p. 3491 - 3494 (1986)
Update date:2022-08-03
Topics:
Enders, Dieter
Papadopoulos, Kyriakos
Rendenbach, Beatrice E.M.
Appel, Rolf
Knoch, Falk
An efficient and highly anti-diastereo-(de=90-100percent) and enantioselective (ee=92-100percent) synthesis of 3,4-disubstituted 5-oxo-alkanoates 3 in good overall chemical yields is described.The procedure involves the asymmetric Michael addition of aldehydes or ketones to enoates via their lithiated SAMP-/RAMP-hydrazones.Both enantiomers are accessible at will.
View Morewebsite:http://www.hanwayschem.com
Contact:+86-18502787239(whatsapp)-
Address:18-1-802, Green Garden, Jianghan District, Wuhan 430023, China
website:http://www.easchem.com
Contact:+86-731-89722861 89722891
Address:2/F-4/Bld Colorful Palace, No.605 Changsha Ave, Yuhua Area Changsha Hunan China.
Ningbo Hi-tech Zone Nice-Synth Chemical Industry Ltd.
Contact:+86-(574)-81110986
Address:No. 1210, Building 3, Wante Business Centre, Hi-tech Zone, Ningbo
Wuxi D-Stone International Co., Ltd.
Contact:+86-510-82740567
Address:21F Hengtong Int'l Centre, 215Zhongshan Road, Wuxi, Jiangsu,China
Hangzhou Zyter Biological & Chemical Technology Co., Ltd.
website:http://www.zyterpharm.com
Contact:+86-18858184290
Address:West Wenyi Road, Cangqian, Yuhang
Doi:10.1016/j.bmcl.2008.06.078
(2008)Doi:10.1016/S0040-4039(00)89130-3
(1985)Doi:10.1039/f19827802073
(1982)Doi:10.1016/S0040-4039(00)84029-0
(1986)Doi:10.1016/S0960-894X(01)00822-8
(2002)Doi:10.1080/10426500801901053
(2008)
