Direct 4-Alkylation of 1,3-Cyclohexanediones via Dianionic Species

DOI: 10.1055/s-1986-31679

Source and publish data:

Synthesis p. 476 - 480 (1986)

Update date:2022-08-04

Topics:

Authors:

Berry, Nicola M.

Darey, Mark C. P.

Harwood, Laurence M.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1055/s-1986-31679

1,3-Cyclohexanediones are directly alkylated at the 4 position via dianionic species generated at -78 deg C using lithium diisopropylamine/hexamethylphosphoric triamide.Acetylation of the reaction products at room temperature yields the 3-acetoxy-6-alkylc

Full text of DOI:10.1055/s-1986-31679

Products guided by the article

Product name:2-Cyclohexen-1-one, 3-(acetyloxy)-5,5-dimethyl-6-(1-methylethyl)-

Cas No:106185-69-7

R&D Labs maybe for 106185-69-7

zhengzhou Triz Pharma-Tech Co., Ltd

website:http://www.Trizpharma-tech.com

Contact:+86-0371-86597269，53392065

Address:High-tech Industrial Development Zone, Zhengzhou City, NO.7 Holly Street
SHIJIAZHUANG CHENSHI IMPORT AND EXPORT CO.,LTD

Contact:+86-311-89871056

Address:RM2017 BUILDING CTIANSHAN GALAXY PLAZA,NO168 CHANGJIANG ROAD,GAOXIN DISTRICT,SHIJIAZHUANG CITY, HEBEI,CHINA
Shao Xing Empire Import&Export CO.,ltd

Contact:86-575-82127757

Address:11#, Weiwu Road, Shangyu Industrial Park, Hangzhou Bay, Hangzhou, Zhejiang Province, China
CHINA MEHECO CORPORATION

Contact:+86-10-67147360/67107388

Address:No.18 Guangming Zhongjie, Chongwen District, Beijing, 100061, China
Shanghai Demand Chemical Co., ltd，China

Contact:86-021-55237578/55239122

Address:Room 3H, No.578, Yingkou Road, Yangpu District, Shanghai, China

Relevant to this article

Stereoselective synthesis of basiliskamides A and B via Prins cyclisation

Doi:10.1016/j.tetlet.2008.07.024
(2008)
Investigations into the chemistry of some 1,6-epithio 1,6-episeleno β-D-glucopyranoses

Doi:10.1071/ch99164
(2000)
Simple methodology for syntheses of porphyrins possessing multiple peripheral substituents with an element of symmetry

Doi:10.1021/jo951870f
(1996)
Intramolecular energy transfer in a tetra-coumarin perylene system: Influence of solvent and bridging unit on electronic properties

Doi:10.1039/b711681k
(2007)
Aromatic amino acid hydroxylase inhibitors. 1. Halogenated phenylalanines.

Doi:10.1021/jm00300a004
(1970)
Convenient Multicomponent One-Pot Synthesis of 2-Iminothiazolines and 2-Aminothiazoles Using Elemental Sulfur Under Aqueous Conditions

Doi:10.1002/ejoc.202100548
(2021)

Article Doi