Carbonic anhydrase inhibitors. Part 43. Schiff bases derived from aromatic sulfonamides: Towards more specific inhibitors for membrane-bound versus cytosolic isozymes

Article abstract of DOI:10.1016/S0223-5234(97)81681-9

Schiff bases were prepared by reaction of sulfanilamide, homosulfanilamide and p-aminoethyl-benzenesulfonamide with substituted benzene- and heterocyclic aldehydes. The compounds were characterized by standard procedures and were assayed as inhibitors of