Synthesis of Z-protected Aib- and Phe(2Me)-containing pentapeptides and their crystal structures

Article abstract of DOI:10.1002/hlca.201400084

A series of pentapeptide derivatives containing α,α- disubstituted α-amino acids have been prepared by a combination of the 'azirine/oxazolone method' and segment condensations. X-Ray crystal-structure determinations of the molecular structures confirmed