Cardiotonic agents. 1. Novel 8-aryl-substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents

DOI: 10.1021/jm00391a012

Source and publish data:

Journal of Medicinal Chemistry p. 1337 - 1342 (1987)

Update date:2022-08-04

Topics:

Authors:

Davey Davey

Erhardt Erhardt

Lumma Jr.

Wiggins Wiggins

Sullivan

Pang Pang

Cantor Cantor

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Article abstract of DOI:10.1021/jm00391a012

Several 8-arylimidazo[1,2-a]pyridines, 8-arylimidazo[1,5-a]pyridines, and 8-arylimidazo[1,5-a]pyridinones were prepared and tested in vitro for potential cardiac inotropic and electrophysiological activity. Selected analogues were further tested in vivo i

Full text of DOI:10.1021/jm00391a012

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