Cardiotonic agents. 1. Novel 8-aryl-substituted imidazo[1,2-a]- and -[1,5-a]pyridines and imidazo[1,5-a]pyridinones as potential positive inotropic agents

DOI: 10.1021/jm00391a012

Source and publish data:

Journal of Medicinal Chemistry p. 1337 - 1342 (1987)

Update date:2022-08-04

Topics:

Authors:

Davey Davey

Erhardt Erhardt

Lumma Jr.

Wiggins Wiggins

Sullivan

Pang Pang

Cantor Cantor

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1021/jm00391a012

Several 8-arylimidazo[1,2-a]pyridines, 8-arylimidazo[1,5-a]pyridines, and 8-arylimidazo[1,5-a]pyridinones were prepared and tested in vitro for potential cardiac inotropic and electrophysiological activity. Selected analogues were further tested in vivo i

Full text of DOI:10.1021/jm00391a012

Products guided by the article

Product name:5,6-dihydro-8-<4-(1H-imidazol-1-yl)phenyl>-3-methylimidazo<1,5-a>pyridine

Cas No:107454-16-0

R&D Labs maybe for 107454-16-0

Shifang Taifeng New Flame Retardant Co., Ltd

Contact:02884721008

Address:tingjiang industrial park, hefeng town
Taiwan Surfactant Corp.

Contact:886 2 2541 0022

Address:8 Fl., No. 11, Sec. 1, Chung Shan North Rd., Taipei, Taiwan R.O.C.
Hangzhou innopharma technology Co,.Ltd.(expird)

Contact:+86-13388601988

Address:Room845,lixin building, moganshan road, hangzhou, china
Zhejiang Newfine Industry Co.,Ltd.

Contact:+86-573-82262042

Address:No.225,Dongqing Road, garoms@163.com
Hangzhou JINLAN Pharm-Drugs Technology Co., Ltd

website:http://www.jlpharms.com

Contact:86-571-86982636

Address:Rm A606, Fuyi Center, jianqiao street

Relevant to this article

Reactions of Azines. 12. Preparation and Reactions of Triphenyl<2-((phenyl(methoxycarbonyl)methylene)hydrazono)propyl>phosphonium Bromide

Doi:10.1021/jo00385a029
(1987)
Escherichia coli allows efficient modular incorporation of newly isolated quinomycin biosynthetic enzyme into echinomycin biosynthetic pathway for rational design and synthesis of potent antibiotic unnatural natural product

Doi:10.1021/ja902261a
(2009)
A Rare and Exclusive Endoperoxide Photoproduct Derived from a Thiacalix[4]arene Crown-Shaped Derivative Bearing a 9,10-Substituted Anthracene Moiety

Doi:10.1002/asia.201600202
(2016)
A Stereoselective Synthesis of (+/-)-cis-α-Irone

Doi:10.1021/jo00386a038
(1987)
New Entry to the C-Glycosilation by means of Carbenoid Displacement Reaction. Its Application to the Synthesis of Showdomycin

Doi:10.1021/ja00244a024
(1987)
Structure-activity relationship studies of phenanthridine-based Bcl-X _L inhibitors

Doi:10.1021/jm8005433
(2008)

Article Doi