Synthesis of Macrocyclic Terpenoids by Intramolecular Cyclization. 12. Total Synthesis of Methyl Ceriferate I, a 14-Membered Ring Sesterterpene from Scale Insects

Article abstract of DOI:10.1021/jo00242a018

Total synthesis of (+/-)-methyl ceriferate I (6), the methyl ester of a cembrane-type sesterterpene isolated from the wax of scale insects, was achieved by means of Wadsworth-Emmons olefination as key step.Three segments, 9, 10, and 11, were connected to