Synthesis and antiinflammatory activities of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones

DOI: 10.1021/jm00394a011

Source and publish data:

Journal of Medicinal Chemistry p. 1995 - 1998 (1987)

Update date:2022-09-26

Topics:

Authors:

Ikuta Ikuta

Shirota Shirota

Kobayashi

Yamagishi

Yamada Yamada

Yamatsu Yamatsu

Katayama

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Article abstract of DOI:10.1021/jm00394a011

A series of 3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-ones was synthesized and evaluated as candidate antiinflammatory/analgesic agents as well as dual inhibitors of prostaglandin and leukotriene synthesis. Some compounds that showed dual inh

Full text of DOI:10.1021/jm00394a011

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Product name:N-ethyl-3-(3,5-di-tert-butyl-4-hydroxybenzylidene)pyrrolidin-2-one

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