Total Synthesis of 7,7-, 10,10-, and 13,13-Difluoroarachidonic Acids

Article abstract of DOI:10.1021/ja00246a027

General methodology is desribed for the synthesis of polyunsaturated fatty acids, in which one of the methylene groups between cis double bonds is replaced by a CF2 group.This is exemplified by the preparation of 7,7-, 10,10-, and 13,13-difluoroarachidoni