Total Synthesis of 7,7-, 10,10-, and 13,13-Difluoroarachidonic Acids

DOI: 10.1021/ja00246a027

Source and publish data:

Journal of the American Chemical Society p. 3684 - 3692 (1987)

Update date:2022-09-26

Topics:

Authors:

Kwok, Pui-Yan

Muellner, Frank W.

Chen, Chien-Kuang

Fried, Josef

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Article abstract of DOI:10.1021/ja00246a027

General methodology is desribed for the synthesis of polyunsaturated fatty acids, in which one of the methylene groups between cis double bonds is replaced by a CF2 group.This is exemplified by the preparation of 7,7-, 10,10-, and 13,13-difluoroarachidoni

Full text of DOI:10.1021/ja00246a027

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