Journal of Medicinal Chemistry p. 999 - 1003 (1987)
Update date:2022-09-26
Topics:
Alabaster, Valerie A.
Campbell, Simon F.
Danilewicz, John C.
Greengrass, Colin W.
Plews, Rhona M.
A series of 4-amino-2-(4-carbamoylpiperidino)-6,7-dimethoxyquinazolines (2) were synthesized and evaluated for α-adrenoceptor affinity and antihypertensive activity.These compounds displayed high binding affinity (Ki, 10-9-10-10
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