Application of the low-valent titanium reductive elimination of 1,6-dibenzoate-2,4-dienes to the total synthesis of 6(E)-5(S)-12(R)-leukotriene B4

Article abstract of DOI:10.1016/S0040-4039(00)60785-2

A stereoselective synthesis of 6(E)-5(S)-12(R)-leukotriene B₄ is described in this paper, using a novel reaction, the low-valent titanium induced reductive elimination of a 1,6-dibenzoate-2,4-diene, for the selective synthesis of the trans-trie