A FACILE RING CLEAVAGE OF CYCLIC KETONES. SYNTHESIS OF 9-(ALKOXYCARBONYLALKYL)PYRIDOPYRIMIDINES

DOI: 10.1016/S0040-4039(01)81033-9

Source and publish data:

Tetrahedron Letters p. 1527 - 1528 (1987)

Update date:2022-07-30

Topics:

Authors:

Huang, Zhi-tang

Wang, Xiao-jun

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Article abstract of DOI:10.1016/S0040-4039(01)81033-9

2-(Hexahydro-2-pyrimidinylidene)cycloalkanones 1 react with ethyl propiolate in alcoholic solution to give 9-(alkoxycarbonylalkyl)-pyrido<1,2-a>pyrimidines 3 via ring cleavage of cyclic ketones.

Full text of DOI:10.1016/S0040-4039(01)81033-9

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