A New Synthesis of 4- and 5-Imidazolethiols

DOI: 10.1021/jo00390a004

Source and publish data:

Journal of Organic Chemistry p. 2977 - 2979 (1987)

Update date:2022-08-03

Topics:

Authors:

Spaltenstein, Andreas

Holler, Tod P.

Hopkins, Paul B.

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Article abstract of DOI:10.1021/jo00390a004

Several examples of a new, mild, and regiocontrolled multistep synthesis of multiply substituted 4- and 5-imidazolethiols are reported.The key step involves a dehydration/cyclization promoted by trimethylsilyl triflate and triethylamine

Full text of DOI:10.1021/jo00390a004

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