Structure-Activity Studies on the C-Terminal Hexapeptide of Substance P with Modifications at the Glutaminyl and Methioninyl Residues

DOI: 10.1021/jm00391a041

Source and publish data:

Journal of Medicinal Chemistry p. 1512 - 1515 (1987)

Update date:2022-08-03

Topics:

Authors:

Poulos, Constantine

Stavropoulos, George

Brown, John R.

Jordan, Christopher C.

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Article abstract of DOI:10.1021/jm00391a041

Analogues of 6>-SP_6-11 have been synthesized in which the SCH3 group of the Met¹¹ side chain is replaced by other functional groups, such as (CH2)2NH2, COOH, CONH2, and COOR, which have basic, acidic, or neutral charac

Full text of DOI:10.1021/jm00391a041

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