A General SRN1-Based Method for Total Synthesis of Unsymmetrically Hydroxylated 2,2'-Binaphtalenes

DOI: 10.1021/jo00226a030

Source and publish data:

Journal of Organic Chemistry p. 3880 - 3883 (1987)

Update date:2022-09-26

Topics:

Authors:

Beugelmans, Rene

Bois-Choussy, Michele

Tang, Qian

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Article abstract of DOI:10.1021/jo00226a030

An S_RN1 reaction between 2'-haloacetophenones and 2'-acetonaphthone derived enolates is the key step in a straightforward one-pot synthesis of unsymetrically substituted 2,2'-binaphtyl derivatives 3a-j.

Full text of DOI:10.1021/jo00226a030

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