Two distinct classes of novel pyrazolinecarboxamides as potent cannabinoid CB1 receptor agonists

DOI: 10.1016/j.bmcl.2010.07.056

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 4992 - 4998 (2010)

Update date:2022-09-26

Topics:

Authors:

Lange, Jos H.M.

Attali, Amos

Van Der Neut, Martina A.W.

Wals, Henri C.

Mulder, Arie

Zilaout, Hicham

Duursma, Ate

Van Aken, Hans H.M.

Van Vliet, Bernard J.

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Article abstract of DOI:10.1016/j.bmcl.2010.07.056

The synthesis and SAR of 3-alkyl-4-aryl-4,5-dihydropyrazole-1-carboxamides 1-23 and 1-alkyl-5-aryl-4,5-dihydropyrazole-3-carboxamides 24-27 as two novel cannabinoid CB₁ receptor agonist classes were described. The target compounds elicited high

Full text of DOI:10.1016/j.bmcl.2010.07.056

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