Heterocycles p. 2649 - 2657 (2008)
Update date:2022-08-04
Topics:
Zieba, Andrzej
Suwinska, Kinga
The reaction of 1-alkyl-4-(phenylamino)quinolinium 3-thiolates (2) with benzoyl chloride leads to 1-alkyl-3-benzoylthio-4-(phenylamino)quinolinium chloride (6). In the presence of DABCO, compounds (6) split off hydrogen chloride yielding 1-alkyl-3-benzoylthio-1,4-dihydro-4-(phenylimino)quinoline (7). Alkylation of 4-(phenylimino)quinoline (7) with ethyl bromide leads to 1-alkyl-3-ethylthio-4-(N-benzoyl-N-phenylamino)quinolinium bromide (10). The structure of the obtained compounds were analyzed using 1H NMR (NOE) and 15N NMR spectral methods. The structure of compound (10a) was confirmed by X-ray analysis. The Japan Institute of Heterocyclic Chemistry.
View MoreContact:+86-21-56338808
Address:799 Dunhuang Road, Putuo
Refine Chemicals Science & Technology Technology Developing Co., Ltd.
Contact:+86-22-87899130
Address:No.12,west keyan road,Tianjin City
website:http://www.lidepharma.com
Contact:+86-25-58409506
Address:11F, Building A1, No.288 North Zhongshan Road, Gulou District, Nanjing,210003, P.R.China.
Shanghai Xinda Pharmaceuticals Co., Ltd.
Contact:86-21-33692333-8008
Address:999 Linxian Road, Jinshan Industrial Park, Shanghai, China
Guangzhou Reachin Chemical Co., Ltd
Contact:+86-20-37087379 ext.604
Address:A122C-1, Tianyuan Plaza, 401 Tianyuan Rd., Tianhe, Guangzhou, China
Doi:10.1111/j.1751-1097.2009.00546.x
(2009)Doi:10.1016/j.bmcl.2018.01.041
(2018)Doi:10.1271/bbb.64.1448
(2000)Doi:10.1016/j.dyepig.2020.108744
(2020)Doi:10.1021/ja306323x
(2012)Doi:10.1021/jo00112a047
(1995)