Organic Process Research and Development p. 230 - 241 (2009)
Update date:2022-08-05
Topics:
Thiel, Oliver R.
Achmatowicz, Michal
Bernard, Charles
Wheeler, Philip
Savarin, Cecile
Correll, Tiffany L.
Kasparian, Annie
Allgeier, Alan
Bartberger, Michael D.
Tan, Helming
Larsen, Robert D.
A practical synthesis of the phthalazine-based p38 MAP kinase inhibitor [(S)-2] was needed for an ongoing program. Vibrational circular dichroism provided the assignment of the absolute stereochemistry of the target compound. The selected synthetic route
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