Synthesis of 9(0)-methano-Δ6(9α)-PGI1: The highly potent carbon analog of prostacyclin

DOI: 10.1016/S0040-4039(00)86021-9

Source and publish data:

Tetrahedron Letters p. 3493 - 3496 (1983)

Update date:2022-08-02

Topics:

Authors:

Shibasaki

Torisawa

Ikegami Ikegami

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/S0040-4039(00)86021-9

A new prostacyclin analog, 9(o)-methano-Δ⁶(9α)-PGI₁, was synthesized by utilizing intramolecular pinacolic coupling reaction as the key step and was shown to be more potent than carbacyclin in inhibition of platelet aggregation.

Full text of DOI:10.1016/S0040-4039(00)86021-9

Products guided by the article

Product name:7-{(1S,2R,3R,5S)-5-Hydroxymethyl-3-(tetrahydro-pyran-2-yloxy)-2-[(E)-3-(tetrahydro-pyran-2-yloxy)-oct-1-enyl]-cyclopentyl}-6-oxo-heptanoic acid methyl ester

Cas No:110456-28-5

R&D Labs maybe for 110456-28-5

Shenyang Mole pharmaceutical Technology Development Co.,Ltd

Contact:+86-24-31204918/13889278616

Address:No.44, wanliutang road, shenhe District of Shenyang
Shanghai Longschem Co.,Ltd

Contact:021-36356756

Address:Room601,Building No.14,280 Yangcheng Road,Shanghai
Shanghai SMEC Trading Co., Ltd.

website:http://www.shanghaismec.com

Contact:+86-21-68811293

Address:ROOM 1101,NO.800 SHANGCHENG RD,SHANGHAI,CHINA
Xi'an Kaixiang Photoelectric Technology Co., Ltd

website:http://www.kxmaterials.com/

Contact:86-29-15991651477

Address:Building 6, Biopharmaceutical Industry R&D Cluster Base, No. 16, Caotang 4th Road, Caotang Science and Technology Industrial Base, High-tech Zone, Xi'an City, Shaanxi Province, China
LIAOYANG WANRONG CHEMICALS COMPANY LIMITED

Contact:86-419-2390789

Address:XINLI VILLAGE , DONG NINGWEI COUNTY,TAIZIHE DISTRICT, LIAOYANG , LIAONING

Relevant to this article

NUCLEOPHILIC DISPLACEMENT OF HYDROGEN IN 4,6-DINITRO-BENZOFUROXAN AND -BENZOFURAZAN. SYNTHESIS OF SOME NOVEL 7-SUBSTITUTED 4,6-DINITRO-BENZOFUROXANS AND -BENZOFURAZANS.

Doi:10.1016/S0040-4039(00)94878-0
(1985)
The synthesis of 5-azido-UTP and UDP-pyridoxal and their effect on the carbamoyl-phosphate synthetase (CPS II) in the mammalian multienzyme polypeptide CAD

Doi:10.1016/0960-894X(96)00452-0
(1996)
SYNTHESIS OF 3-CYANO-4-ARYL-5-ETHOXYCARBONYL-6-METHYL-3,4-DIHYDROPYRIDINE-2-THIONES

Doi:10.1007/BF00505906
(1985)
Doi:10.1021/ja00304a072
(1985)
Copper-Catalysed Cascade Synthesis of Imidazolidine-Benzothiazole and Imidazolidine-Tetrazole Hybrid Heterocycles from Bis-thioureas by a Desulfurisation Strategy

Doi:10.1002/ejoc.201501096
(2015)
One-pot synthesis of enantiomerically pure N-protected allylic amines from N-protected α-amino esters

Doi:10.3762/bjoc.12.94
(2016)

Article Doi