The synthesis of 5-azido-UTP and UDP-pyridoxal and their effect on the carbamoyl-phosphate synthetase (CPS II) in the mammalian multienzyme polypeptide CAD

DOI: 10.1016/0960-894X(96)00452-0

Source and publish data:

Bioorganic and Medicinal Chemistry Letters p. 2513 - 2518 (1996)

Update date:2022-08-02

Topics:

Authors:

Zhu, Li-Min

Carrey, Elizabeth A.

Read Full Text PDF DownLoad Join now for total 90,000,000 free articles

Article abstract of DOI:10.1016/0960-894X(96)00452-0

5-azidouridine-5'-triphosphate and UDP-pyridoxal have been synthesized using modified synthetic methods. The two synthetic UTP analogues, with commercially available analogues and chemicals have been tested for their effect on CPSase II in the mammalian multienzyme polypeptide CAD. Structure activity relationships are discussed.

Full text of DOI:10.1016/0960-894X(96)00452-0

Products guided by the article

Product name:uridine diphosphopyridoxal

Cas No:97654-04-1

R&D Labs maybe for 97654-04-1

Lanzhou SchiffChem Co.,Ltd

Contact:86-931-8272767

Address:Room 602, No.461, Nanchang Road, Chengguan District, Lanzhou City, China PRC
Shanghai Standard Biotech Co., Ltd.

Contact:+86-18502101150

Address:Room 103, Building 2nd, NO.720, Cailun Road , Pudong District, Shanghai, China
H&Y International Group Ltd

Contact:+86-571-86491666

Address:SHI XIANG ROAD
Feis International Trade Co,. Ltd

Contact:13961823444-18235944442

Address:Wuxi jiangsu
Laizhou City Laiyu Chemical CO.,Ltd

Contact:+86-535-2719337/2719339

Address:Chenggang road zhuyou laizhou City Shangdong China

Relevant to this article

(H⁺,K⁺)-ATPase inhibiting 2-[(2-pyridylmethyl)sulfinyl]benzimidazoles. 4. A novel series of dimethoxypyridyl-substituted inhibitors with enhanced selectivity. The selection of pantoprazole as a clinical candidate

Doi:10.1021/jm00084a010
(1992)
α-Amino Acids as Chiral Educts for Asymmetric Products. The Synthesis of α'-Amino-α,β-ynones

Doi:10.1021/jo00221a004
(1985)
BOTRYODIPLODIN: A MYCOTOXIN FROM PENICILLIUM ROQUEFORTI. REACTION WITH AMINO-PYRIMIDINES, AMINO-PURINES AND 2'-DEOXYNUCLEOSIDES

Doi:10.1016/S0040-4020(01)96415-4
(1985)
Optimizing of 2,3-diarylindenes as fluorescent estrogens: Variation of the acceptor group, ortho substitution of the 2-ring, and C-1 methylation

Doi:10.1021/jm00117a014
(1988)
Pseudosymmetry and Bioisosterism in Biaryl Pyridyl Competitive Histamine H2-Receptor Antagonists

Doi:10.1021/jm00149a015
(1985)
The reaction of trialkylstannylmethyllithium with α,β-epoxy ketones and α-chloro ketones

Doi:10.1016/S0040-4020(01)86394-8
(1991)

Article Doi