Studies on the monoamine oxidase (MAO)-catalyzed oxidation of phenyl- substituted 1-methyl-4-phenoxy-1,2,3,6-tetrahydropyridine derivatives: Factors contributing to MAO-A and MAO-B selectivity

DOI: 10.1021/jm00011a010

Source and publish data:

Journal of Medicinal Chemistry p. 1904 - 1910 (1995)

Update date:2022-08-02

Topics:

Authors:

Wang Wang

Castagnoli Jr.

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Article abstract of DOI:10.1021/jm00011a010

The structural parameters responsible for the substrate and inhibitor selectivities of the monoamine oxidases (MAO) A and B remain poorly understood. This situation has improved somewhat with structure-activity studies that have been performed on nuclear-

Full text of DOI:10.1021/jm00011a010

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