SOLID-PHASE SYNTHESIS OF PROTECTED OLIGONUCLEOTIDE BLOCKS APPLICATIONS TO BLOCK CONDENSATION ON A POLYMER SUPPORT AND SYNTHESIS OF A 3'-MODIFIED OLIGONUCLEOTIDES

DOI: 10.1016/S0040-4020(01)89930-0

Source and publish data:

Tetrahedron p. 59 - 68 (1987)

Update date:2022-08-04

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Authors:

Iwai, Shigenori

Koizumi, Makoto

Ikehara, Morio

Ohtsuka, Eiko

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Article abstract of DOI:10.1016/S0040-4020(01)89930-0

The solid-phase synthesis of protected oligodeoxy-ribonucleotide blocks using a new phosphoramidate linkage between the 3'-terminal nucleoside and the polymer support is described.The oligonucleotide block cleaved from the support contains a phosphodieste

Full text of DOI:10.1016/S0040-4020(01)89930-0

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