A Ring-Closing Metathesis Approach to Cyclic a,b-Dehydroamino Acids
FULL PAPERS
yield: 17.5 mg (90%). The ee was determined by HPLC to
be 81% (Chiralcel AD-H column; hexane/2-propanol,
98:2).
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Acknowledgements
This research has been financially supported (in part)by the
Council for Chemical Sciences of the Netherlands Organiza-
tion for Scientific Research (CW-NWO). Christien A. Schor-
tinghuis (Chiralix B.V., Nijmegen, The Netherlands)is kindly
acknowledged for the LC-MS measurements. Kaspar Koch
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Adv. Synth. Catal. 2008, 350, 95 – 106
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