SYNTHESIS OF THE FRAGMENT GlcNAc-α(1-P-6)-GlNAc OF THE CELL WALL POLYMER OF STAPHYLOCOCCUS LACTIS HAVING REPEATING N-ACETYL-D-GLUCOSAMINE PHOSPHATE UNITS

Article abstract of DOI:10.1016/S0040-4039(00)85450-7

The monofunctional phosphitylating reagents chloro-β-cyanoethyl-N,N-diisopropylamino-phosphoramidite (3) and salicylchlorophosphite (4) have been applied towards the introduction of an α-(1-6) interglycosidic phosphodiester bond between two properly-protected N-acetyl-D-glucosamine units.Evidence will be presented to show that 4 gives a higher yield of the requirede dimer than 3.