Improved General Method of Ortho Alkylation of Phenols Using Alkyl Isopropyl Sulfide, Sulfuryl Chloride and Triethylamine. An Expedient Synthesis of Representative Oxygen Heterocycles and (2R,4'R,8'R)-α-Tocopherol

Article abstract of DOI:10.1021/jo00233a047

Functionalized alkyl groups have been introduced regioselectively into the ortho position of phenols via <2,3> sigmatropic rearrangement of isopropylphenoxysulfonium alkylide, providing a quite efficient synthesis of precursors for chromans, chromens, coumarins, and d-α-tocopherol.