[18F]Fluoroamines via ring-opening of N-Cbz-2-methylaziridine with [18F]-fluoride

DOI: 10.1016/j.tetlet.2008.11.074

Source and publish data:

Tetrahedron Letters p. 544 - 547 (2009)

Update date:2022-07-29

Topics:

Authors:

Vasdev, Neil

van Oosten, Erik M.

Stephenson, Karin A.

Zadikian, Nonik

Yudin, Andrei K.

Lough, Alan J.

Houle, Sylvain

Wilson, Alan A.

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Article abstract of DOI:10.1016/j.tetlet.2008.11.074

A highly regioselective method was developed for ring-opening benzyloxycarbonyl (Cbz)-protected 2-methylaziridine with [¹⁸F]-labelled fluoride. Following catalytic hydrogenation, 1-[¹⁸F]fluoro-2-propanamine ([¹⁸F]1) and 2-

Full text of DOI:10.1016/j.tetlet.2008.11.074

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