Synthesis and Antiviral Activity of Various 3'-Azido Analogues of Pyrimidine Deoxyribonucleosides against Human Immunodeficiency Virus (HIV-1, HTLV-III/LAV)

DOI: 10.1021/jm00397a011

Source and publish data:

Journal of Medicinal Chemistry p. 336 - 340 (1988)

Update date:2022-09-26

Topics:

Authors:

Lin, Tai-Shun

Guo, Ji-Yu

Schinazi, Raymond F.

Chu, Chung K.

Xiang, Jia-Ning

Prusoff, Willian H.

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Article abstract of DOI:10.1021/jm00397a011

Various 3'-azido analogues of pyrimidine deoxyribonucleosides have been synthesized and tested against human immunodeficiency virus (HIV-1, HTLV-III/LAV) in human peripheral blood mononuclear cells.Among these compounds, the 3'-azido analogues of thymidin

Full text of DOI:10.1021/jm00397a011

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