Stereoselective total synthesis of 5(S), 6(R), 15(S)-trihydroxy-7(E), 9(E), 11(Z), 13(E)-eicosatetraenoic acid (Lipoxin A)

DOI: 10.1016/S0040-4039(97)10471-3

Source and publish data:

Tetrahedron Letters p. 143 - 146 (1998)

Update date:2022-08-03

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Authors:

Yadav Yadav

Barma Barma

Dutta, Dinah

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Article abstract of DOI:10.1016/S0040-4039(97)10471-3

A stereoselective synthesis of the title compound from D-xylose using zinc mediated deoxygenation of 4-hydroxy-2-butenoic acid moiety and base induced double elimination of 4,5-epoxy allyl chloride as key steps is described.

Full text of DOI:10.1016/S0040-4039(97)10471-3

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