Journal of the Chemical Society. Chemical communications p. 1775 - 1776 (1985)
Update date:2022-07-29
Topics: Synthesis Inhibitors Phosphodiesterase
Bolton, Richard E.
Moody, Christopher J.
Rees, Charles W.
Tojo, Gabriel
The pyrrolo<3,2-e>indole phosphodiesterase inhibitors PDE-I (1) and PDE-II (2) have been synthesised from isovanilin by a route which involves construction of both pyrrole rings by thermolysis of azidoacrylates readily derived from benzaldehydes.
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