Indium trichloride mediated cleavage of acetonides in the presence of acid-labile functional groups - Enhancing the synthetic utility of 1,3-dioxolanyl-substituted 1,2-oxazines

Article abstract of DOI:10.1055/s-0028-1083628

Indium trichloride in an acetonitrile-water mixture chemoselectively cleaved the isopropylidene acetals of various 1,3-dioxolanyl-substituted 1,2-oxazines as well as carbohydrate derivatives. Deprotection of acetonides can be achieved in substrates suscep