Stereoselective synthesis of chiral IBR2 analogues

DOI: 10.1021/jo802607f

Source and publish data:

Journal of Organic Chemistry p. 2018 - 2027 (2009)

Update date:2022-08-05

Topics:

Authors:

Qiu, Xiao-Long

Zhu, Jiewen

Wu, Guikai

Lee, Wen-Hwa

Richard Chamberlin

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Article abstract of DOI:10.1021/jo802607f

Two stereoselective routes were developed to synthesize optically pure IBR2 analogues 1-16. The first features addition of N-Boc-3-bromoindole 26 to the sulfinamide 25, providing a 1:1 ratio of the separable diasteroisomers 27 and 28 in good yield. In a s

Full text of DOI:10.1021/jo802607f

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